Download PDF
Synthesis 1985; 1985(12): 1125-1129
DOI: 10.1055/s-1985-31448
communication
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Alkaline Sodium Borohydride-Promoted Reductive Alkylation of ß-Aminomercurials: Synthesis of 1,5-Functionalized Amines

José Barluenga* , Pedro J. Campos, Joaquín López-Prado, Gregorio Asensio
  • *Departamento de Química Orgánica, Facultad de Química, Universidad de Oviedo, 33071-Oviedo, Spain
Further Information

Publication History

Publication Date:
27 September 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

ß-Aminoalkyl radicals generated by alkaline sodium borohydride reduction of aminomercurials react with electron-deficient olefins in an one pot procedure. These reactions allow direct synthesis of 5-aminonitriles and 5-aminoesters. 1,5-Diamines and aminoalcohols were also prepared by reduction of the former compounds.