Download PDF
Synthesis 1989; 1989(1): 66-69
DOI: 10.1055/s-1989-27156
communication
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

The Chemistry of N-Substituted Benzotriazoles; Part II.1 The Preparation of Tertiary Amines Containing Tertiary-Alkyl Groups from Ketones, Secondary Amines, and Organometallic Reagents

Alan R. Katritzky* , Zbigniew Najzarek, Zofia Dega-Szafran
  • *Department of Chemistry, University of Florida, Gainesville, FL 32611, USA
Further Information

Publication History

Publication Date:
27 September 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

The preparation of important pharmaceutically active highly branched tertiary amines by the reaction of Grignard reagents with adducts of cyclic ketones, benzotriazole (or pyrazole) and secondary amines is far superior to previously available routes.