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Synthesis 1989; 1989(6): 466-468
DOI: 10.1055/s-1989-27293
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Selected Methods for the Oxidation of 1,1,1-Trichloro-2-alkanols. An Efficient Modification Using Chromic Acid

Carlo Gallina* , Cesare Giordano
  • *Centro di Studio per la Chimica del Farmaco, Dipartimento di Studi Farmaceutici, Università "La Sapienza", Roma, Italy
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Publication Date:
17 September 2002 (online)

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The effectiveness of thirteen largely applied procedures has been checked in the oxidation of 1,1,1-trichloropropan-2-ol. A new, simple, and efficient modification using chromic acid has been found for the preparation of representative trichloromethyl ketones.