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Synthesis 1994; 1994(4): 361-362
DOI: 10.1055/s-1994-25474
short paper
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A New Convenient Synthesis of Methyl 4-Oxoalkanoates

Oleg G. Kulinkovich* , Victor L. Sorokin
  • *Department of Chemistry, Belarussian State University, Fr. Skorina Avenue 4, 220050 Minsk, Belarus'
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Publication Date:
17 September 2002 (online)

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Methyl 4-oxoalkanoates have been obtained in good yields by treatment of 1, 2-dichloro-2-alken-4-ones with sodium carbonate in methanol followed by acid-catalyzed hydrolysis of the intermediate 5-alkyl-2,2-dimethoxy-2, 3-dihydrofurans.