Synthesis 1994; 1994(12): 1403-1405
DOI: 10.1055/s-1994-25700
short paper
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An Efficient Route to α,β-Epoxy Ketones of High Enantiomerical Purity

L. Pégorier* , Y. Petit, A. Mambu, M. Larchevêque
  • *Laboratoire de Synthèse Organique, UA 1381 du CNRS; ENSCP, 11 rue Pierre et Marie Curie; F-75231, Paris Cedex 05, France
Further Information

Publication History

Publication Date:
25 April 2002 (online)

Acylepoxides were obtained in high enantiomeric purity (ee = 92-99%) by addition of organolithium or Grignard reagents to enantiomerically pure methyl or ethyl 2,3-epoxypropanoates at low temperature ( - 85°C)