Subscribe to RSS
DOI: 10.1055/s-2004-829026
© Georg Thieme Verlag Stuttgart · New York
Paraneoplastische neurologische Autoimmunerkrankungen
Paraneoplastic neurological autoimmune diseasesPublication History
eingereicht: 30.4.2004
akzeptiert: 22.7.2004
Publication Date:
05 August 2004 (online)
Glossar
anti-VGCC = Antikörper gegen spannungsabhängige Ca-Kanäle
CRMP5/CV2-Antikörper = Antikörper gegen „Collapsin response mediator Protein”
EEG = Elektro-Enzephalogramm
FDG-PET = Positronenemissions-Tomographie mit Fluor-Deoxyglukose
Hu-Antikörper = benannt nach dem Index-Patienten Hull
LEMS = Lambert-Eaton-Myastheniesyndrom
LP = Lumbalpunktion
Ma-/Ta-Antikörper = benannt nach der Indexpatientin Taylor
MRT = Magnetresonanz-Tomographie
PKD = Paraneoplastische Kleinhirndegeneration
PLE = Paraneoplastische limbische Enzephalitis
PNS Euronetwork = Paraneoplastic neurological syndromes Euro- network
SCLC = kleinzelliges Bronchial-Karzinom
SN = sensible Neuronopathie
Yo-Antikörper = benannt nach der Index-Patientin Young
Literatur
- 1 Bain P G, Motomura M, Newsom-Davis J. et al . Effects of intravenous immunoglobulin on muscle weakness and calcium-channel autoantibodies in the Lambert-Eaton myasthenic syndrome. Neurology. 1996; 47 678-683
- 2 Dalmau J, Gultekin S H, Voltz R. et al . Ma1, a novel neuronal and testis specific protein, is recognized by the serum of patients with paraneoplastic neurologic disorders. Brain. 1999; 122 27-39
- 3 Darnell R B, Posner J B. Paraneoplastic syndromes involving the nervous system. N Engl J Med. 2003; 349 1543-1554
- 4 Graus F, Cordon-Cardo C, Posner J B. Neuronal antinuclear antibody in sensory neuronopathy from lung cancer. Neurology. 1985; 35 538-543
- 5 Graus F, Dalmau J, Rene R. et al . Anti-Hu antibodies in patients with small-cell lung cancer: association with complete response to the therapy and improved survival. J Clin Oncol. 1997; 15 2866-2872
- 6 Graus F, Delattre J Y, Antoine J C, Dalmau J, Giometto B, Grisold W, Honnorat J, Sillevis S mitt P, Vedeler C, Verschuuren J, Vincent A, Voltz R. for the Paraneoplastic Neurological Syndrome Euronetwork . Recommended diagnostic criteria for paraneoplastic neurological syndromes. J Neurol Neurosurg Psychiatry. 2004; in Druck
- 7 Graus F, Keime-Guibert F, Rene R. et al . Anti-Hu-associated paraneoplastic encephalomyelitis: analysis of 200 patients. Brain. 2001; 124 1138-1148
- 8 Gultekin S H, Rosenfeld M R, Voltz R. et al . Paraneoplastic limbic encephalitis: tumor association, neurological symptoms, and immunological findings in 50 patients. Brain. 2000; 123 1481-1494
- 9 Honnorat J, Antoine J C, Derrington E. et al . Antibodies to a subpopulation of glial cells and a 66 kDa developmental protein in patients with paraneoplastic neurological syndromes. J Neurol Neurosurg Psychiatry. 1996; 61 270-278
- 10 Linke R, Schröder M, Helmberger Th, Voltz R. Antibody-positive paraneoplastic neurological syndromes: The value of CT and FDG-PET imaging for tumor diagnosis. Neurology. 2004; 63 282-286
- 11 Maddison P, Newsom-Davis J, Mills K R, Souhami R L. Favourable prognosis in Lambert-Eaton myasthenic syndrome and small-cell lung carcinoma. Lancet. 1999; 353 117-118
- 12 Mason W P, Graus F, Lang B. et al . Small-cell lung cancer, paraneoplastic cerebellar degeneration and the Lambert-Eaton myasthenic syndrome. Brain. 1997; 120 1279-1300
- 13 Molinuevo J L, Graus F, Serrano C. et al . Utility of anti-Hu antibodies in the diagnosis of paraneoplastic sensory neuropathy. Ann Neurol. 1998; 44 976-980
- 14 Posner J B. Paraneoplastic syndromes. Contemporary Neurological Series, FA Davis In: Posner JB. Neurologic complications of cancer 1995: 353-385
- 15 Rojas I, Graus F, Keime-Guibert F. et al . Long-term clinical outcome of paraneoplastic cerebellar degeneration and anti-Yo antibodies. Neurology. 2000; 55 713-715
- 16 Rosenfeld M R, Eichen J G, Wade D F. et al . Molecular and clinical diversity in paraneoplastic immunity to Ma proteins. Ann Neurol. 2001; 50 339-348
- 17 Voltz R, Carpentier A F, Rosenfeld M R. et al . P/Q-type voltage-gated calcium channel antibodies in paraneoplastic disorders of the central nervous system. Muscle Nerve. 1999; 22 119-122
- 18 Voltz R, Gultekin S H, Rosenfeld M R. et al . A serologic marker of paraneoplastic limbic and brain-stem encephalitis in patients with testicular cancer. N Engl J Med. 1999; 340 1788-1795
- 19 Voltz R. Paraneoplastic neurological syndromes: An update on diagnosis, pathogenesis and therapy. The Lancet Neurology. 2002; 1 294-305
- 20 Yu Z, Kryzer T J, Griesmann G E. et al . CRMP-5 neuronal autoantibody: marker of lung cancer and thymoma-related autoimmunity. Ann Neurol. 2001; 49 146-154
Prof. Dr. Raymond Voltz
Institut für Klinische Neuroimmunologie, Klinikum Großhadern
81366 München
Phone: 089/70954439 oder -0,
Fax: 089/70957435 oder -4782
Email: rvoltz@nro.med.uni-muenchen.de