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Synthesis 2005(5): 703-704
DOI: 10.1055/s-2005-861869
DOI: 10.1055/s-2005-861869
SHORTPAPER
© Georg Thieme Verlag Stuttgart · New York
The First Synthesis of Cynandione A
Further Information
Received
22 September 2004
Publication Date:
14 March 2005 (online)
Publication History
Publication Date:
14 March 2005 (online)
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Abstract
Cynandione A was prepared from acetylbenzoquinone by conjugate addition, acylation and demethylation.
Keywords
cynandione A - acetylbenzoquinone - conjugate addition - acylation - demethylation
- 1
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References
We assign the structure of the monoacetate based on the mass spectral fragmentation of M - H2O, which we believe arises from the interaction between the acetyl group and the hydroxyl on the neighboring ring (Figure [2] ). This fragmentation is also observed in compounds 4, 5 and 1.