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Planta Med 1997; 63(3): 265-266
DOI: 10.1055/s-2006-957669
DOI: 10.1055/s-2006-957669
Letters
© Georg Thieme Verlag Stuttgart · New York
Protective Effect of Curcuminoids on Epidermal Skin Cells under Free Oxygen Radical Stress
Further Information
Publication History
1996
1996
Publication Date:
04 January 2007 (online)
![](https://www.thieme-connect.de/media/plantamedica/199703/lookinside/thumbnails/10.1055-s-2006-957669-1.jpg)
Abstract
Curcuminoids from Curcuma longa L. (Zingiberaceae) protected normal human keratinocytes from hypoxanthine/ xanthine oxidase injury. Since curcuminoids synergistically inhibited nitroblue tetrazolium reduction, a decrease in superoxide radical formation leading to lower levels of cytotoxic hydrogen peroxide was proposed as an explanation for this protective effect.