Synthesis 2007(1): 75-80  
DOI: 10.1055/s-2006-958926
PAPER
© Georg Thieme Verlag Stuttgart · New York

A Convenient Synthesis of Alkenyl-Substituted Glycidonitriles and Glycidates

Anna Gadaj, Andrzej Jończyk*
Warsaw University of Technology, Faculty of Chemistry, Koszykowa St. 75, 00662 Warsaw, Poland
Fax: +48(22)6282741; e-Mail: anjon@ch.pw.edu.pl;
Further Information

Publication History

Received 20 June 2006
Publication Date:
12 December 2006 (online)

Abstract

α-Chloronitriles or α-chloroesters reacted with α,β-unsaturated carbonyl compounds in the presence of powdered sodium hydroxide, in ethereal solvents, giving alkenyl-substituted glycidonitriles or esters. The straightforward process affords nitriles in particularly high yields.