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Horm Metab Res 1983; 15(3): 116-119
DOI: 10.1055/s-2007-1018646
DOI: 10.1055/s-2007-1018646
Hyperosmolar Non-Ketotic Diabetic Coma in the Nonhuman Primate: A First Report
Further Information
Publication History
1981
1982
Publication Date:
14 March 2008 (online)
Summary
Diabetes mellitus was diagnosed in an aged bonnet macaque (Macaca radiata). Six months later the monkey was found comatose. Laboratory findings of extreme hyperglycemia, hyperosmolality, and glycosuria without ketonuria were consistent with a diagnosis of hyperosmolar, non-ketotic diabetic coma (NKC). Further laboratory studies disclosed very low levels of immunoreactive insulin and depressed free fatty acid values. Growth hormone and cortisol levels were within normal limits.
Key-Words:
Diabetes Mellitus - Nonhuman Primate - Hyperosmolality - Coma