Pankreatitis nach ERCP -Ursachen und Vermeidung

Die Pankreatitis stellt mit einer Häufigkeit von 2 bis 9 % die häufigste Komplikation der ERCP dar (Freeman et al., 2004, Foster et al., 2007). Im Folgenden werden im Rahmen einer Literatur-Übersicht die Risikofaktoren der post- ERCP-Pankreatitis dargestellt. Anschließend wird über Strategien zur Vermeidung dieser Komplikation berichtet.

Literatur

• 1 Andriulli A., Leandro G., Niro G., Mangia A., Festa V., Gambassi G.. Pharmacological treatment can prevent pancreatic injury after ERCP: a meta-analysis, Gastrointest.  Endosc.. 2000;  51 1-7
• 2 Arnold C. J., Benz C., Martin R. W., Adamek E. H., Riemann F. J.. Endoscopic papillary balloon dilatation vs. sphincterotomy for removal of common bile duct stones: a prospective randomized pilot study,.  Endoscopy. 2001;  33 563-567
• 3 Cohen S., Bacon R. B., Berlin A. J., Fleischer D., Hecht A. G., Loehrer J. P.. Sr. National Institutes of Health State-of-the-Science Conference statement: ERCP for diagnosis and therapy, January 14-16, 2002, Gastrointest.  Endosc.. 2002;  56 809; 
• 4 Cotton B. P., Lehman G., Vennes J., Geenen E. J., Russell C. R., Meyers C. W.. Endoscopic sphincterotomy complications and their management: an attempt at consensus, Gastrointest.  Endosc.. 1991;  37 393; 
• 5 DiSario A. J., Freeman L. M., Bjorkman J. D., MacMathuna P., Petersen B., Sherman S.. Endoscopic balloon dilatation compared to sphincterotomy (EDES) forextraction of bile duct stones: preliminary results , Gastrointest.  Endosc.. 1997;  45
• 6 Foster E., Leung J.. Pharmacotherapy for the prevention of post-ERCP pancreatitis Am.  J. Gastroenterol.. 2007;  102 55; 
• 7 Freeman L. M., Nelson B. D., Sherman S., Haber B. G., Herman E. M., Dorsher J P.. Complications of endoscopic biliary sphincterotomy.  N. Eng. J. Med.. 1996;  335
• 8 Freeman L. M., DiSario A. J., Nelson B. D., Fennerty B. M., Lee G. J., Bjorkman J. D.. Risk factors for post-ERCP pancreatitis: a prospective, multicenter study, Gastrointest.  Endosc.. 2001;  54 434; 
• 9 Freeman L. M., Guda M. N.. Prevention of post-ERCP pancreatitis: a comprehensive review Gastrointest.  Endosc.. 2004;  59 864; 
• 10 Li S. Z., Pan X., Zhang J. W., Gong B., Zhi C. F., Guo G. X., Li M. P., Fan N. Z., Sun S. W., Shen Z. Y., Ma R. S., Xie F. W., Chen H. M., Li Q. Y.. Effect of octreotide administration in the prophylaxis of post-ERCP pancreatitis and hyperamylasemia: a multicenter, placebo-controlled, randomized clinical trial.  Am. J. Gastroenterol.. 2007;  102 46-51
• 11 Moreto M., Zaballa M., Cosado I., Merino O., Rueda M., Ramirez K.. Transdermal glyceryl trinitrate for prevention of post-ERCP pancreatitis: a randomized double-blind trial. Gastrointest.  Endosc.. 2003;  57
• 12 Murray B., Carter R., Imrie C., Evans S., OŽSuilleabhain C.. Diclofenac reduces the incidence of acute pancreatitis after endoscopic retrograde cholangio-pancreaticography.  Gastroenterology. 2003;  124
• 13 Raty S., Sand J., Pulkkinen M., Matikainen M., Nordback I.. Post-ERCP pancreatitis: reduction by routine antibiotics, J. Gastrointest.  Surg. 2001;  339
• 14 Sherman S., Troiano P. F., Hawes H. R., Lehman A. G.. Sphincter Oddi manometry: decreased risk of clinical pancreatitis with use of a modified aspirating catheter, Gastrointest.  Endosc.. 1990;  36
• 15 Sudhindran S., Bromwich E., Edwards R. P.. Prospective randomized double-blind placebo-controlled trial of glyceryl trinitrate in endoscopic retrograde cholangiopancreaticography-induced pancreatitis.  Br. J. Surg.. 2001;  88
• 16 Trap R., Adamsen S., Hart-Hansen O., Henriksen M.. Severe and fatal complications after diagnostic and therapeutic ERCP: A prospective series of claims to insurance covering public hospitals.  Endoscopy. 1999;  31
• 17 Vandervoort J., Soetikno M. R., Tham C. T., Wong C. R., Ferrari Jr. A. P., Montes H.. Risk factors for complications after performance of ERCP.  Gastrointest. Endosc.. 2002;  56
• 18 Wehrmann T., Stergiou N., Schmitt T., Dietrich F. C., Seifert H.. Reduced risk for pancreatitis after endoscopic microtransducer manometry of the sphincter of Oddi: a randomized comparison with the perfusion manometry technique.  Endoscopy. 2003;  35