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Am J Perinatol 1996; 13(4): 203-205
DOI: 10.1055/s-2007-994364
ORIGINAL ARTICLE

© 1996 by Thieme Medical Publishers, Inc.

Prenatal Detection of the Separation of the Great TOE, TOE Syndactyly, and Large Bilateral Choroid Plexus Cysts in a Fetus with Trisomy 18

Chih-Ping Chen, Fen-Fen Liu, Sheau-Wen Jan, Chao-Wen Chen, Kuo-Gon Wang, Chung-Chi Lan
  • Department of Obstetrics and Gynecology, Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan, Republic of China
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Publication Date:
04 March 2008 (online)

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ABSTRACT

Prenatal sonographic presentation of toe deformities is associated with fetal aneu-ploidies. This report presents a second-trimester fetus with large bilateral choroid plexus cysts, clenched hands, separation of the great toe, toe syndactyly, abnormal double maternal serum biochemical screening results, and trisomy 18. We suggest a careful ultrasound screening of the fetal limbs and other organs once a choroid plexus cyst has been identified. If abnormal sonographic findings are present, or if the results of the maternal serum biochemical screening are abnormal, karyotyping should be recommended.

Keywords

Toe deformity - biochemical screening - choroid plexus cyst - trisomy 18