PDF herunterladen
Tierarztl Prax Ausg K Kleintiere Heimtiere 2017; 45(01): 40-45
DOI: 10.15654/TPK-160018
Kasuistik
Schattauer GmbH

Magnetic resonance imaging and clinical findings in carbon monoxide intoxication in dogs

A case series Artikel in mehreren Sprachen: deutsch | English
Malgorzata Kolecka
1   Klinikum Veterinärmedizin, Klinik für Kleintiere – Chirurgie, Justus-Liebig-Universität Gießen
,
Kerstin von Pückler
1   Klinikum Veterinärmedizin, Klinik für Kleintiere – Chirurgie, Justus-Liebig-Universität Gießen
,
Steven De Decker
2   Department of Clinical Science and Services, Royal Veterinary College, University of London, Hatfield, United Kingdom
,
Stefano Cortellini
2   Department of Clinical Science and Services, Royal Veterinary College, University of London, Hatfield, United Kingdom
,
Gabriel Wurtinger
1   Klinikum Veterinärmedizin, Klinik für Kleintiere – Chirurgie, Justus-Liebig-Universität Gießen
,
Martin J. Schmidt
1   Klinikum Veterinärmedizin, Klinik für Kleintiere – Chirurgie, Justus-Liebig-Universität Gießen
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Eingegangen: 07. Januar 2016

Akzeptiert nach Revision: 09. März 2016

Publikationsdatum:
08. Januar 2018 (online)

Auch verfügbar auf
    Lizenzen und Reprints

Summary

This paper presents magnetic resonance imaging (MRI) findings of three dogs after carbon monoxide intoxication. In the first and second cases, MRI changes were confined to both caudate nuclei and in the first case also to the putamen as bilaterally symmetric diffuse homogenous T2 and FLAIR hyperintense, T1 hypointense lesions. No contrast enhancement was seen. In the third case MRI revealed multiple areas of hyperintensity bilaterally on T2 and FLAIR as well as ill-defined areas within the frontal, parietal and occipital grey matter. The caudal colliculi, globus pallidus, substantia nigra and central area of the thalamus showed bilaterally hyperintense lesions on T2w and FLAIR with moderate enhancement after intravenous contrast administration.

Keywords

Carbon monoxide - smoke intoxication - poisoning - encephalopathy
 

  • Literatur

  • 1 Abelsohn A, Sandborn MD, Jessiman BJ, Weir E. Identifying and managing adverse environmental health effects: 6. Carbon monoxide poisoning. CMAJ 2002; 166: 1685-1690.
    PubMedGoogle Scholar
  • 2 Coburn R F. Mechanism of carbon monoxide toxicity. Prev Med 1979; 8: 310-322.
    CrossrefPubMedGoogle Scholar
  • 3 Falini A, Barkovich AJ, Calabrese G, Origgi D, Triulzi F, Scotti G. Progressive brain failure after diffuse hypoxic ischemic brain injury: a serial MR and proton MR spectroscopic study. Am J Neuroradiol 1998; 19: 648-652.
    PubMedGoogle Scholar
  • 4 Geraldo AF, Silva C, Neutel D, Neto LL, Albuquerque L. Delayed leukoencephalopathy after acute carbon monoxide intoxication. J Radiol Case Rep 2014; 8: 1-8.
    CrossrefPubMedGoogle Scholar
  • 5 Gorman D, Drewry A, Haung YL, Sames C. The clinical toxicology of carbon monoxide. Toxicology 2003; 187: 25-38.
    CrossrefPubMedGoogle Scholar
  • 6 Hamcan S, Akgun V, Yilmaz O, Turan A. Isolated cerebellar damage caused by carbon monoxide intoxication. BMJ Case Reports. 2013 doi: DOI: 10.1136/bcr-2013–201647.
    CrossrefPubMedGoogle Scholar
  • 7 Kent M, Creevy KE, deLahunta A. Clinical and neuropathological findings of acute carbon monoxide toxicity in chihuahuas following smoke inhalation. J Am Anim Hosp Assoc 2010; 46: 259-264.
    CrossrefPubMedGoogle Scholar
  • 8 Kim I-H, Chang K-H, Song IC, Kim KH, Kwon BJ, Kim H-C, Kim JH, Han MH. Delayed encephalopathy of acute carbon monoxide intoxication: diffusivity of cerebral white matter lesions. Am J Neuroradiol 2003; 24: 1592-1597.
    PubMedGoogle Scholar
  • 9 Lapresle J, Fardeau M. The central nervous system and carbon monoxide poisoning II. Anatomical study of brain lesions following intoxications with carbon monoxide (22 cases). In carbon monoxide poisoning. Prog Brain Res 1967; 24: 31-74.
    PubMedGoogle Scholar
  • 10 Okeda R, Funata N, Takan O, Miyazaki Y, Higashino F, Yokoyama K, Manabe M. The pathogenesis of carbon monoxide encephalopathy in the acute phase – physiological and morphological correlation. Acta Neuro path 1981; 54: 1-10.
    PubMedGoogle Scholar
  • 11 Peney DG. Acute carbon monoxide poisoning: animal models – a review. Toxicology 1990; 62: 123-160.
    CrossrefPubMedGoogle Scholar
  • 12 Prokop LD, Chichkova R. Carbon monoxide intoxication: An updated review. J Neurol Sci 2007; 262: 122-130.
    CrossrefPubMedGoogle Scholar
  • 13 Rodkey FL, O’Neil JD, Collisom H A, Uddin DA. Relative affinity of hemoglobin S and hemoglobin A for carbon monoxide and oxygen. Clin Chem 1974; 20: 83-84.
    PubMedGoogle Scholar
  • 14 Schmidt MJ, Kramer M. Metabolisch-toxische Enzephalopathien. In: MRT-Atlas ZNS-Befunde bei Hund und Katze. Stuttgart: Enke; 2015: 197-212.
    Google Scholar
  • 15 Singhal AB, Topcuoglu MA, Koroshetz WJ. Diffusion MRI in three types of anoxic encephalopathy. J Neurol Sci 2002; 196: 37-40.
    CrossrefPubMedGoogle Scholar
  • 16 Stephen RA, Donal SW, Siobhain OB, Michael CR, Daniel CJ. Carbon monoxide poisoning: Novel magnetic resonance imaging pattern in the acute setting. J Emerg Med 2012; 5: 30.
    PubMedGoogle Scholar
  • 17 Teksam M, Casey SO, Michel E, Liu H, Truwit CL. Diffussion-weighted MR imaging findings in carbon monoxide poisoning. Neuroradiol 2002; 4: 109-113.
    PubMedGoogle Scholar
  • 18 Thom MD, Taber RL, Mendiguren II, Clark JM, Hardy KR, Fisher AB. Delayed neuropsychologic sequelae after carbon monoxide poisoning: prevention by treatment with hyperbaric oxygen. Ann Emerg Med 1995; 25: 474-480.
    CrossrefPubMedGoogle Scholar
  • 19 Varon J, Marik PE, Fromm Jr RE, Gueler A. Carbon monoxide poisoning: a review for clinicians. J Emerg Med 1999; 17: 87-93.
    CrossrefPubMedGoogle Scholar