Synlett 2016; 27(02): 267-271
DOI: 10.1055/s-0035-1560595
letter
© Georg Thieme Verlag Stuttgart · New York

(S)-Pyrrolidine-Containing Chiral Manganese(III)–Salalen and –Salan Complexes as Catalysts for the Asymmetric Henry Reaction

Pramod Kumar
Department of Chemistry, University of Delhi, Delhi-110007, India   Email: ssingh1@chemistry.du.ac.in
,
ManMohan Singh Chauhan
Department of Chemistry, University of Delhi, Delhi-110007, India   Email: ssingh1@chemistry.du.ac.in
,
Geeta Devi Yadav
Department of Chemistry, University of Delhi, Delhi-110007, India   Email: ssingh1@chemistry.du.ac.in
,
Surendra Singh*
Department of Chemistry, University of Delhi, Delhi-110007, India   Email: ssingh1@chemistry.du.ac.in
› Author Affiliations
Further Information

Publication History

Received: 29 September 2015

Accepted after revision: 24 October 2015

Publication Date:
01 December 2015 (online)


Abstract

Chiral Mn(III)–salalen and –salan complexes derived from (S)-proline have been used as catalysts for the asymmetric Henry (nitro-aldol) reaction. We have also used this methodology for a variety of substrates to afford nitroaldol products in 40–94% yields with 25–92% ee.

Supporting Information