Use of Taxanes in Metastatic HER2-negative Breast Cancer – a Status Report

Oleg Gluz; Cornelia Kolberg-Liedtke; Frederik Marmé; Marc Thill

doi:10.1055/a-1126-4247

Geburtshilfe und Frauenheilkunde, Inhaltsverzeichnis

CC BY-NC-ND 4.0 · Geburtshilfe Frauenheilkd 2020; 80(04): 399-409
DOI: 10.1055/a-1126-4247

GebFra Science

Review/Übersicht

Georg Thieme Verlag KG Stuttgart · New York

Einsatz von Taxanen beim metastasierten HER2-negativen Mammakarzinom – ein Statusreport

Artikel in mehreren Sprachen: English | deutsch

Oleg Gluz

¹Westdeutsche Studiengruppe, Mönchengladbach, Germany

²Ev. Krankenhaus Bethesda, Brustzentrum Niederrhein, Mönchengladbach, Germany

³Uniklinik Köln, Köln, Germany

,

Cornelia Kolberg-Liedtke

⁴Charité – Universitätsmedizin Berlin, Frauenklinik, Berlin, Germany

,

Frederik Marmé

⁵Universitätsklinikum Mannheim, Frauenklinik, Mannheim, Germany

,

Marc Thill

⁶Agaplesion Markus Krankenhaus, Klinik für Gynäkologie, Frankfurt am Main, Germany

› Institutsangaben

Abstract

Zusammenfassung

Das wichtigste Therapieziel bei der Behandlung von Patientinnen mit metastasiertem Mammakarzinom ist die Erhaltung oder gar Verbesserung der Lebensqualität. Vor diesem Hintergrund sollte die Indikation zur Chemotherapie möglichst zurückhaltend gestellt werden. Falls die Indikation zur palliativen Chemotherapie besteht, ist die Wirkstoffklasse der Taxane als Therapieoption etabliert. Die aktualisierten Leitlinien der Arbeitsgemeinschaft Gynäkologische Onkologie (AGO), Kommission Mamma, der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe (DGGG) und der Deutschen Krebsgesellschaft e. V. (DKG) geben Empfehlungen, in welcher Therapiesituation welches der zugelassenen Taxane im metastasierten Setting mit höchstmöglicher Evidenz eingesetzt werden kann.

Schlüsselwörter

Mammakarzinom - metastasiert - Chemotherapie - Taxane

Volltext

Referenzen

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