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Synthesis 2021; 53(14): 2342-2366
DOI: 10.1055/a-1394-7511
DOI: 10.1055/a-1394-7511
short review
Recent Advances in the Synthesis of Heterocycles by the Aza-Wittig Reaction
Abstract
The formation of the C=N bond in recent studies on heterocyclic compounds via the aza-Wittig reaction is reviewed. Furthermore, two different strategies for the formation of heterocyclic compounds, including intermolecular and intramolecular aza-Wittig reactions are described. The primary aim of this review is to provide up-to-date information on the application of the aza-Wittig reaction in the synthesis of a wide range of N-containing heterocyclic compounds in the chemical literature since 2010.
1 Introduction
2 Mechanism of the Staudinger and Aza-Wittig Reactions
3 Intramolecular Aza-Wittig Reaction
4 Intermolecular Aza-Wittig Reaction
5 Conclusion
Key words
aza-Wittig reaction - iminophosphorane - N-containing heterocycles - Staudinger reaction - cyclizationPublikationsverlauf
Eingereicht: 13. Dezember 2020
Angenommen nach Revision: 18. Februar 2021
Accepted Manuscript online:
18. Februar 2021
Artikel online veröffentlicht:
29. April 2021
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