Samarium-Promoted Homocoupling of Benzaldehydes and In Situ Condensation with Esters Under the Catalysis of Cuprous Iodide

Abstract

A novel C–H functionalization method was successfully explored by a reductive three molecule coupling of benzaldehydes and esters mediated by samarium and cuprous iodide; thus, the diarylmethanol skeletons were afforded readily via an in situ esterification in one-pot. Substrates including a variety of esters and different benzaldehydes were investigated, and the desired products were readily obtained in moderate to good yields under mild conditions.

Key words

samarium - cuprous iodide - benzaldehyde - reductive coupling - diarylmethanol

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