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DOI: 10.1055/a-2045-7314
Posterior Lamellar Corneal Graft (DSAEK) in an Aphakic and Congenital Aniridic Single Eye: A Case Report Presenting a New Surgical Procedure
Posteriore lamelläre Hornhauttransplantation (DSAEK) in einem aphakischen und angeborenen Aniridikum-Single-Eye: ein Fallbericht, der einen neuen chirurgischen Eingriff präsentiert
Background/Introduction
Trends in types of corneal grafts have hugely changed during the last 10 years [1] and primary or secondary corneal endothelial decompensation is the main cause of posterior lamellar grafts. DMEK (Descemet Membrane Endothelial Keratoplasty) surgery became more popular because clinical data shows many advantages: better UCVA (Uncorrected Visual Acuity) or CVA (Corrected Visual Acuity), an acceptable amount of endothelial cells lost, lower allograft rejection rate compared to Descemet stripping endothelial keratoplasty (DSAEK) and PK (Penetrating Keratoplasty) [2], and a better survival rate after 5 years (97.5%) compared to DSAEK (76.45%) and PK (54.6%) [3].
Congenital aniridia is a rare ocular disease (1 : 60 000 to 1 : 90 000) [4], [5], [6]. The presence of an aniridia-associated keratopathy (AAK) increases with age and can contribute to visual impairment. In these cases, endothelial cell loss is usually secondary to cataract and/or glaucoma surgery [7]; however, it could also be primary. Penetrating keratoplasty has a poor prognosis because of the recurrence of the AAK and graft rejection occurs in 64% of the cases [8], [9].
In this case report, we propose to perform a new surgical procedure with a modified shape DSAEK to treat a congenital aniridic and aphakic single eye with endothelial cell decompensation.
Publication History
Received: 16 October 2022
Accepted: 18 January 2023
Article published online:
25 April 2023
© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
Georg Thieme Verlag KG
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