Subscribe to RSS
DOI: 10.1055/a-2387-1845
Self-assembling peptide improves the efficacy and safety of endoscopic band ligation for colonic diverticular bleeding
Introduction
Endoscopic band ligation (EBL) for colonic diverticular bleeding (CDB) is useful treatment, offering lower rebleeding rates, reduced need for interventional radiology, and shorter length of hospital stay, compared with clip therapy [1] [2] However, it requires some time to attach an EBL device after the bleeding source has been identified, which can cause problems with prolonged bleeding [1] [2] [3]. Furthermore, continuous bleeding can cause visibility to be impaired, and make it difficult to identify the bleeding source and potentially worsen the patient's condition.
Self-assembling peptide is indicated for hemostasis of oozing bleeding [4], but a case report exists of self-assembling peptide solution temporarily stopping spurting bleeding [5]. We considered that self-assembling peptide might help solve the problem.
Publication History
Received: 07 May 2024
Accepted after revision: 31 July 2024
Article published online:
15 October 2024
© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
-
References
- 1 Kobayashi K, Nagata N, Furumoto Y. et al. Effectiveness and adverse events of endoscopic clipping versus band ligation for colonic diverticular hemorrhage: a large-scale multicenter cohort study. Endoscopy 2022; 54: 735-744 DOI: 10.1055/a-1705-0921. (PMID: 34820792)
- 2 Setoyama T, Ishii N, Fujita Y. Endoscopic band ligation (EBL) is superior to endoscopic clipping for the treatment of colonic diverticular hemorrhage. Surg Endosc 2011; 25: 3574-3578 DOI: 10.1007/s00464-011-1760-8. (PMID: 21638178)
- 3 Ishii N, Setoyama T, Deshpande GA. et al. Endoscopic band ligation for colonic diverticular hemorrhage. Gastrointest Endosc 2012; 75: 382-387 DOI: 10.1016/j.gie.2011.07.030. (PMID: 21944311)
- 4 Fedrica B, Rolf K-N, Kristina F. et al. PuraStat in gastrointestinal bleeding: results of a prospective multicentre observational pilot study. Surg Endosc 2022; 36: 2954-2961
- 5 Yamaguchi D, Ishida S, Nomura T. et al. Endoscopic hemostasis of spurting colonic diverticular bleeding using the combination of self-assembling peptide solution and endoscopic band ligation. Endoscopy 2023; 55: E418-E419 DOI: 10.1055/a-2008-0599. (PMID: 36758630)