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Synfacts 2009(4): 0460-0460  
DOI: 10.1055/s-0028-1087861
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

RCM Reactions with a Ruthenium Micellar Catalyst

Contributor(s): Yasuhiro Uozumi, Takao Osako
B. H. Lipshutz*, S. Ghorai
University of California, Santa Barbara, USA
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Publication History

Publication Date:
23 March 2009 (online)

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Significance

Micellar ruthenium catalyst 5 was prepared by esterification of the free phenolic group in amphiphile 1 with acid 2, followed by the treatment with ruthenium complex 4. Catalyst 5 promoted the ring-closing metathesis of dienes 6 in water to afford the corresponding cyclic olefins 7 in 82-99% yield.