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Synlett 2009(9): 1520-1521  
DOI: 10.1055/s-0029-1217180
SPOTLIGHT
© Georg Thieme Verlag Stuttgart ˙ New York

Iodoxybenzene (PhIO2)

Cai Zhang*
College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. of China
e-Mail: stezh64@swu.edu.cn;
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Publication History

Publication Date:
18 May 2009 (online)

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Introduction

Iodoxybenzene (PhIO2, mp 230 ˚C) is the first organic compound of iodine(V) prepared by Willgerodt 100 years ago. [¹] Specifically, it can be prepared by disproportionation of iodosylbenzene under steam distillation. [²] Ten years ago iodoxybenzene has been used for the synthesis of cadalenquinone, [³a] unsaturated carbonyl compounds [³b-c] , oxodienes, [³d-e] , epoxides, [³f] quinine imines, [³g] and sulfones. [³h] In this Spotlight recent applications using PhIO2 in organic syntheses are summarized.