Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000131.xml
Synfacts 2009(7): 0773-0773
DOI: 10.1055/s-0029-1217295
DOI: 10.1055/s-0029-1217295
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag
Stuttgart ˙ New York
Ir-Catalyzed N-Heterocyclization for Enantio-selective Synthesis of Noranabasamine
L. Miao, S. C. DiMaggio, H. Shu, M. L. Trudell*
University of New Orleans, USA
Further Information
Publication History
Publication Date:
22 June 2009 (online)
Significance
Yamaguchi’s iridium-catalyzed N-heterocyclization reaction of diols with primary amines is utilized for the short total synthesis of both enantiomers of noranabasamine. The absolute configuration of this natural product is also established.