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Synfacts 2010(2): 0130-0130  
DOI: 10.1055/s-0029-1219034
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of Plaunotol

Contributor(s): Philip Kocienski
Y. Hirata, T. Yukawa, N. Kashihara, Y. Nakao*, T. Hiyama*
Kyoto University, Japan
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Publikationsverlauf

Publikationsdatum:
21. Januar 2010 (online)

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Significance

A detailed study of the scope of the nickel-catalyzed carbocyanation of alkynes with allyl cyanides culminated in the synthesis of plaunotol, a natural product active against Helicobacter pylori.