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Synfacts 2010(2): 0216-0216  
DOI: 10.1055/s-0029-1219069
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Copper-Catalyzed Arene C-H Activation and Cross-Coupling

Contributor(s): Paul Knochel, Tobias Thaler
H.-Q. Do, O. Daugulis*
University of Houston, USA
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Publikationsverlauf

Publikationsdatum:
21. Januar 2010 (online)

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Significance

An efficient, highly regioselective one-pot protocol for the activation and cross-­coupling of aromatic C-H bonds was developed. Various electron-rich heteroarenes and arenes could thus be coupled with electron-poor arenes possessing more than one electron-withdrawing group.