Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000131.xml
Synfacts 2010(2): 0206-0206
DOI: 10.1055/s-0029-1219144
DOI: 10.1055/s-0029-1219144
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag
Stuttgart ˙ New York
Enantioselective In(III)-Catalyzed Ketone-Ene Reaction
J.-F. Zhao, T.-B. W. Tjan, B.-H. Tan, T.-P. Loh*
Nanyang Technological University, Singapore
Further Information
Publication History
Publication Date:
21 January 2010 (online)
![](https://www.thieme-connect.de/media/synfacts/201002/lookinside/thumbnails/10.1055-s-0029-1219144-1.jpg)
Significance
Building upon their previous work (J. Am. Chem. Soc. 2008, 130, 16492) the authors report on an indium(III)-pybox-based catalyst system of enhanced reactivity for the ketone-ene reactions of trifluoropyruvate, providing homoallylic alcohols with a quaternary stereocenter in high yield and enantioselectivity.