A Practical One-Pot Transformation of Triphenylphosphine Oxide to Triphenylphosphine by Reduction of in situ Generated Triphenylphosphine Dichloride

Abstract

One-pot transformation of triphenylphosphine oxide to triphenylphosphine was achieved by the reaction of triphenylphosphine oxide with oxalyl chloride, which led to the formation of triphenylphosphine dichloride, and subsequent reduction of triphenylphosphine dichloride with a combination of aluminum-catalytic metal salt.

Key words

triphenylphosphine - triphenylphosphine oxide - reduction - aluminum - multi redox system

References and Notes

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19

Recently, the authors reported electrochemical reduction of triphenylphosphine dichloride to triphenylphosphine. Yano, T.; Kuroboshi, M.; Tanaka, H. Tetrahedron Lett. in press.

22

Triphenylphosphine oxide 2 was obtained by the hydrolysis of triphenylphosphine dichloride 3 in the workup procedure.