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Synfacts 2010(4): 0435-0435  
DOI: 10.1055/s-0029-1219621
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Catalytic Asymmetric Cycloaddition of Allene-Dienes

Contributor(s): Hisashi Yamamoto, Kimberly Griffin
A. Z. González, F. D. Toste*
University of California, Berkeley, USA
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Publication History

Publication Date:
22 March 2010 (online)

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Significance

The majority of gold(I)-catalyzed enantioselective reactions employ bis(gold)-­phosphine complexes. Interestingly, the authors here use chiral monodentate phosphite-like ligands to catalyze cycloadditions of allene-dienes. As an extension of previous work, this paper utilizes ligand-controlled reactivity to produce [4+2]-cycloaddition products of allene-dienes.