Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000131.xml
Synfacts 2010(5): 0547-0547
DOI: 10.1055/s-0029-1219673
DOI: 10.1055/s-0029-1219673
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag
Stuttgart ˙ New York
Asymmetric Hydrogenation of N-Protected Indoles Catalyzed by Iridium Complexes
A. Baeza, A. Pfaltz*
University of Basel, Switzerland
Further Information
Publication History
Publication Date:
22 April 2010 (online)

Significance
In this work, several iridium complexes were developed to catalyze asymmetric hydrogenation of N-protected indoles which provided various indolines bearing C2 or C3 chirality in high yield and enantioselectivity. These catalysts were not only efficient but also practical in air and moisture stability.