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Synfacts 2010(5): 0582-0582
DOI: 10.1055/s-0029-1219678
DOI: 10.1055/s-0029-1219678
Metal-Mediated Synthesis
© Georg Thieme Verlag
Stuttgart ˙ New York
Bromine-Lithium Exchange on Cyano-Substituted Arenes Using Microreactors
A. Nagaki, H. Kim, H. Usutani, C. Matsuo, J.-i. Yoshida*
Kyoto University, Japan
Further Information
Publication History
Publication Date:
22 April 2010 (online)
Significance
The dynamics of microflow systems allow the performance of reactions that cannot be carried out under standard conditions. A bromine-lithium exchange on arenes bearing sensitive cyano groups could be successfully implemented with a microflow system.