Synfacts 2010(9): 1083-1083  
DOI: 10.1055/s-0030-1257983
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Reductive Homocoupling of Haloarenes in Water with Palladium Nanoparticles

Contributor(s): Yasuhiro Uozumi, Tsubasa Muto
A. Monopoli*, V. Calò, F. Ciminale, P. Cotugno, C. Angelici, N. Cioffi, A. Nacci*
Università degli Studi Aldo Moro, Bari, Italy
Further Information

Publication History

Publication Date:
23 August 2010 (online)

Significance

Palladium nanoparticles were generated in situ from palladium diacetate in the presence of tetrabutylammonium hydroxide (TBAOH), and glucose as reductant, which promoted reductive homocoupling of bromo- and chloroarenes in water to give the corresponding biaryls in up to 95% yield (13 examples).