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Synlett 2010(13): 2041-2044  
DOI: 10.1055/s-0030-1258540
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© Georg Thieme Verlag Stuttgart ˙ New York

Asymmetric CuH-Catalyzed 1,4-Reductions in Water at Room Temperature

Shenlin Huang, Karl R. Voigtritter, John B. Unger, Bruce H. Lipshutz*
Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, USA
Fax: +1(805)8938265; e-Mail: lipshutz@chem.ucsb.edu;
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Publikationsverlauf

Received 18 June 2010
Publikationsdatum:
02. August 2010 (online)

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Abstract

Taking advantage of micellar catalysis in water, asymmetric hydrosilylation reactions can now be conducted at ambient temperatures using water, and only water, as the global medium.

Key words

copper hydride - hydrosilylations - reduction - asymmetric catalysis - micellar catalysis - green chemistry

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12

Lipshutz, B. H.; Ghorai, S. University of California, Santa Barbara, CA, in preparation. TPGS-750-M = polyoxyethanyl-α-tocopheryl succinate.