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Synfacts 2010(11): 1214-1214
DOI: 10.1055/s-0030-1258714
DOI: 10.1055/s-0030-1258714
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag
Stuttgart ˙ New York
Synthesis of Kapakahine E
V. R. Espejo, J. D. Rainier*
University of Utah, Salt Lake City, USA
Further Information
Publication History
Publication Date:
21 October 2010 (online)
Significance
The kapakahine family of natural products was isolated from the marine sponge Cribrochalina olemda. Kapakahine E was shown to be active against P388 murine leukemia cells (IC50 = 5.0 µg/mL).