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Synfacts 2010(11): 1217-1217
DOI: 10.1055/s-0030-1258717
DOI: 10.1055/s-0030-1258717
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag
Stuttgart ˙ New York
Synthesis of (+)-Norsecurinine
M. R. Medeiros, J. L. Wood*
Yale University, New Haven and Colorado State University, Fort Collins, USA
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
21. Oktober 2010 (online)
Significance
(+)-Norsecurinine belongs to the Securinega alkaloid series isolated from the plant family Euphorbiaceae. These compounds exhibit a broad spectrum of biological activities and contain synthetically challenging indolizidine or pyrrolizidine motifs. An enantioselective synthesis of (+)-norsecurinine is described.