Synfacts 2010(11): 1296-1296  
DOI: 10.1055/s-0030-1258725
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

α-Selective Nickel-Catalyzed Hydroalumination of Terminal Alkynes

Contributor(s): Paul Knochel, Andreas J. Wagner
F. Gao, A. H. Hoveyda*
Boston College, Chestnut Hill, USA
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Publikationsverlauf

Publikationsdatum:
21. Oktober 2010 (online)

Significance

A nickel-catalyzed hydroalumination reaction of terminal alkynes is described, ­affording selectively α-vinylaluminum reagents. The so generated organoaluminum compounds smoothly react with various electrophiles in high yields.