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Synfacts 2011(2): 0197-0197  
DOI: 10.1055/s-0030-1259235
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Coupling of N-Tosylhydrazone, Terminal Alkyne, and Aryl Halide

Contributor(s): Paul Knochel, Tobias Thaler
L. Zhou, F. Ye, Y. Zhang, J. Wang*
Peking University, Beijing, P. R. of China
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Publication History

Publication Date:
19 January 2011 (online)

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Significance

A highly expedient method for the direct synthesis of benzhydryl acetylene derivatives via a three-component coupling involving N-tosylhydrazones, terminal alkynes, and aryl ­halides has been developed.