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Synfacts 2011(2): 0230-0230  
DOI: 10.1055/s-0030-1259368
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Aqueous Suzuki-Miyaura Coupling with Palladium Nanoparticles/BMI-TFSI

Contributor(s): Yasuhiro Uozumi, Tsubasa Muto
Y. Oda, K. Hirano, K. Yoshii, S. Kuwabata, T. Torimoto, M. Miura*
Osaka University, Suita, Japan Science and Technology Agency, Kawaguchi and Nagoya University, Japan
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Publication History

Publication Date:
19 January 2011 (online)

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Significance

Palladium nanoparticles (average particle size ca. 2.2 nm) were prepared by a ­sputter deposition of palladium onto 1-butyl-3-methylimidazolium bis(trifluoromethanesulfonyl)-imide (BMI-TFSI). The palladium nanoparticles in BMI-TFSI (Pd/BMI-TFSI) catalyzed the Suzuki-Miyaura coupling of aryl halides 1 with aryl boronic acids 2 in the presence of cesium carbonate in water to give the corresponding biaryls 3 in up to 99% yield (17 examples).