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Synfacts 2011(5): 0544-0544  
DOI: 10.1055/s-0030-1259786
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

CuBr-Catalyzed Synthesis of Benzofurans and Indoles

Contributor(s): Paul Knochel, Andreas K. Steib
L. Zhou, Y. Shi, Q. Xiao, Y. Liu, F. Ye, Y. Zhang, J. Wang*
Peking University, Beijing, P. R. of China
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Publikationsdatum:
15. April 2011 (online)

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Significance

The paper describes a novel ­copper-catalyzed reaction for the synthesis of benzofurans and indoles using terminal alkynes and N-tosylhydrazones. The N-tosylhydrazones are easily obtained from the corresponding ortho-hydroxy- or ortho-aminobenzaldehydes.