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Synfacts 2011(8): 0893-0893  
DOI: 10.1055/s-0030-1260724
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Ni-Catalyzed Cross-Coupling of Aryltrimethylammonium Iodides

Contributor(s): Paul Knochel, Andreas J. Wagner
L.-G. Xie, S.-X. Wang*
University of Science and Technology of China, Hefei, P. R. of China
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Publication History

Publication Date:
20 July 2011 (online)

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Significance

A highly efficient process for the Ni-catalyzed coupling of aryltrimethylammonium iodides with aryl- and alkylzinc reagents has been developed. This protocol benefits from a large substrate scope and good functional group tolerance.