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Synfacts 2011(9): 0928-0928  
DOI: 10.1055/s-0030-1260987
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of Lactimidomycin

Contributor(s): Steven V. Ley, Philippa B. Cranwell
D. Gallenkamp, A. Fürstner*
Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany
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Publikationsdatum:
19. August 2011 (online)

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Significance

Lactimidomycin exhibits antiproliferative properties against various tumors, including a highly invasive human breast carcinoma. It is also a lead structure in the quest for small molecule inhibitors of cell migration, which can help prevent metastasis within the body.