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Synfacts 2011(11): 1220-1220
DOI: 10.1055/s-0031-1289216
DOI: 10.1055/s-0031-1289216
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag
Stuttgart ˙ New York
One-Pot Domino Ring Opening/C-N Bond Formations
M. K. Ghorai*, Y. Nanaji, A. K. Yadav
Indian Institute of Technology, Kanpur, India
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
19. Oktober 2011 (online)

Significance
Tetrahydroquinolines are biologically relevant molecules that have attracted a great deal of synthetic interest. While there are numerous methods of the construction of such structural motifs, the synthesis of enantiopure products from easily obtained chiral starting materials remains an attractive strategy. Furthermore, the synthesis of such compounds in a domino one-pot fashion is noteworthy and allows for ease of synthesis.