Download PDF
Synfacts 2011(11): 1204-1204  
DOI: 10.1055/s-0031-1289221
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Pd-Catalyzed Chemo- and Regioselective Allylic Alkylation

Contributor(s): Mark Lautens, Lei Zhang
J.-P. Chen, Q. Peng, B.-L. Lei, X.-L. Hou*, Y.-D. Wu*
Shanghai Institute of Organic Chemistry, Peking University Shenzhen Graduate School, Beijing and The Hong Kong University of Science and Technology, Kowloon, P. R. of China
Further Information

Publication History

Publication Date:
19 October 2011 (online)

    Permissions and Reprints

Significance

A tunable palladium-catalyzed allylic alkylation was realized. The authors propose that by changing the counterion of the base from Li+ to K+ the reaction became selective for branched products with high diastereoselectivity.