RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000131.xml
Synfacts 2011(12): 1336-1336
DOI: 10.1055/s-0031-1289333
DOI: 10.1055/s-0031-1289333
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag
Stuttgart ˙ New YorkCatalyst-Controlled Diastereo- and Enantioselective Hydrogenation
M. Akashi, N. Arai, T. Inoue, T. Ohkuma*
Hokkaido University, Sapporo and Nippon Soda Co., Ltd., Odawara, Japan
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
18. November 2011 (online)

Significance
A diastereoselective reduction of aryl ketones catalyzed by ruthenium is reported. Under rapid enolization-protonation of the substrate in the presence of a base, the strong catalyst preference for one out of four possible transition states also successfully rendered a dynamic kinetic resolution.