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Synfacts 2011(12): 1310-1310  
DOI: 10.1055/s-0031-1289429
Synthesis of Materials and Unnatural Products
© Georg Thieme Verlag Stuttgart ˙ New York

A One-Pot Route to 3-Vinyl Coumarins

Contributor(s): Timothy M. Swager, Jan M. Schnorr
J. Gordo, J. Avó, A. J. Parola, J. C. Lima, A. Pereira*, P. S. Branco*
Universidade Nova de Lisboa and Universidade de Évora, Portugal
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Publication History

Publication Date:
18 November 2011 (online)

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Significance

Coumarins are one of the most widely used classes of fluorescent dyes and have found applications in organic light-emitting diodes, optical brighteners, and fluorescent labels. The authors present a convenient one-pot synthesis of 3-vinylcoumarins 3. The π-electron system can be further extended by Heck coupling with aryl halides leading to a variety of substituted coumarin dyes 4.