Syntheses of Fawcettimine-Type Lycopodium Alkaloids Utilizing the Pauson–Khand Reaction

Abstract

The asymmetric total syntheses of some fawcettimine-type Lycopodium alkaloids, utilizing an intramolecular Pauson–Khand reaction as the key step, are described.

1 Introduction

2 First Asymmetric Total Syntheses of Lycoposerramine-C and Phlegmariurine A

3 First Asymmetric Total Synthesis of Huperzine Q

4 Total Syntheses of Fawcettimine and Fawcettidine

5 Conclusion

Key words

alkaloids - total synthesis - asymmetric synthesis - fawcettimine - Pauson–Khand reaction

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