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Synfacts 2013; 9(1): 0014
DOI: 10.1055/s-0032-1317718
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of Akt Inhibitor GDC-0068

Contributor(s):
Philip Kocienski
Further Information

Publication History

Publication Date:
17 December 2012 (online)

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Key words

GDC-0068 - serine/threonine kinase - Akt inhibitor - Favorskii ring contraction - Noyori asymmetric transfer hydrogenation - pyrimidine N-oxide rearrangement