Z-Selective Dimerization of Aromatic Terminal Alkynes Catalyzed by an Iridium(I)–N-Heterocyclic Carbene–Phosphine System

Abstract

The development of an iridium-catalyzed regio- and stereoselective dimerization process has enabled the formation of (Z)-enyne products. More specifically, low catalyst loadings of an iridium(I) complex, featuring a bulky N-heterocyclic carbene–phosphine ligand combination, has been successfully employed in this selective head-to-head dimerization of terminal alkynes via C–H activation.

Key words

alkynes - enynes - dimerization - C–H activation - iridium

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