One-Pot Procedures for the Formation of Secondary Aryl Amines from Nitro Aryls

Abstract

Strategies for the one-pot formation of secondary aryl amines from the corresponding nitro aryls by utilizing reductive amination procedures are discussed. The extension of this chemistry where a Suzuki–Miyaura cross-coupling is conducted between a boronic acid and bromonitrobenzene prior to the reductive amination in one-pot is also presented.

Key words

one pot - Suzuki–Miyaura cross-coupling - reductive monoalkylation - biaryl - secondary amine

• References

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