CAN-Catalyzed Rapid C–O Bond Formation towards α-Aminoxylation of Ketones

Abstract

A simple and efficient approach towards α-oxyaminated ketones has been developed through CAN-catalyzed C–O bond formation with 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO). The environmentally friendly transformation is practical due to the use of commercial available catalyst, easy operating procedures, the broad substrate scope, and short reaction time.

Key words

CAN - ketone - α-aminoxylation - C–O bond formation - TEMPO

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