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Synlett 2017; 28(18): 2478-2482
DOI: 10.1055/s-0036-1588451
DOI: 10.1055/s-0036-1588451
cluster
Reactivity of Seven-Membered-Ring trans-Alkenes with Electrophiles
This research was supported by the National Science Foundation (CHE-1362709). J.R.S. was supported by a Margaret Strauss Kramer Fellowship from the NYU Department of ChemistryWeitere Informationen
Publikationsverlauf
Received: 10. April 2017
Accepted after revision: 10. Mai 2017
Publikationsdatum:
21. Juni 2017 (online)
Published as part of the Cluster Silicon in Synthesis and Catalysis
Abstract
Seven-membered-ring trans-alkenes containing a silicon–oxygen bond reacted rapidly with oxygen gas and electron-deficient alkenes and alkynes to give products with high selectivity. Addition of an electron-donating substituent or incorporating additional strain increased the reactivity by over two orders of magnitude. These results indicate that release of strain is not the only driving force for reactivity.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1588451.
- Supporting Information
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References and Notes
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