Synfacts, Table of Contents Synfacts 2018; 14(05): 0455DOI: 10.1055/s-0037-1609498 Synthesis of Natural Products and Potential Drugs © Georg Thieme Verlag Stuttgart · New York Synthesis of GDC-0810 Contributor(s): Philip Kocienski Recommend Article Abstract Buy Article Key words Key wordsGDC-0810 - selective estrogen receptor degrader - diastereoselective addition - Grignard reagent - Felkin–Anh model - asynchronous concerted E1 elimination - tetrasubstituted alkene Full Text